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Figure 1 (Left) A nine-month-old (TT) presented with a one-day history of fever, irritability, poor feeding, respiratory distress, and poor ventricular function by echocardiography. Death ensued within four hours of presenting to the emergency room. Formalin-fixed cardiac tissue (TTRV1) was positive for adenovirus by polymerase chain reaction (PCR), as demonstrated by the 308 bp PCR product—the same size seen with the adenovirus type 5 control. The 135 bp band is the k-ras PCR product. Note that Patient ALH’s right ventricular endomyocardial biopsy was negative for the adenoviral PCR product but amplifies the 135 bp k-ras product. (Right) Southern blot and hybridization with a radiolabeled adenovirus probe.
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