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Figure 1 (A) Mean ± SD myocardial phosphocreatine to adenosine-triphosphate (PCr/ATP) ratios in type 2 diabetic patients (solid bar) and controls (open bar). *p < 0.01. (B) Representative phosphorus-31 magnetic resonance spectroscopy (31P-MRS) obtained at rest from the anterior left ventricular wall of a patient (upper panel) and healthy subject (lower panel). The peaks of PCr, ATP, and inorganic phosphate (Pi) plus 2,3-diphospho-glycerate (2,3-DPG) are identified in the upper panel. Myocardial PCr/ATP ratios, as presented below the 31P-MRS, were corrected for partial saturation effects and blood-ATP contamination, and line broadening of 15 Hz was applied.
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