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Figure 5 Influence of the intracoronary systolic pressure gradients on the discrepancy between mean and diastolic fractional flow reserve (FFR) measurements, expressed as the ratio mean FFR/diastolic FFR. At baseline the discrepancy between the techniques is minimal and is not influenced by systolic gradients. Conversely, during dobutamine challenge a significant inverse relationship between intracoronary systolic gradient and the defined discrepancy develops, being maximal in those patients who developed negative systolic intracoronary pressure gradients.





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