Advertisement






Click here for more guidelines.
CME Topic Collections Past Issues Search Current Issue Home
     

J Am Coll Cardiol, 2003; 42:2172, doi:10.1016/j.jacc.2003.10.005
© 2003 by the American College of Cardiology Foundation
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Haas, D. C.
Right arrow Articles by Pickering, T. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Haas, D. C.
Right arrow Articles by Pickering, T. G.

LETTER TO THE EDITOR

Depression as another possibleexplanation for worse outcomesin myocardial infarction during off-hours

Donald C. Haas, MD, MPH*, Karina W. Davidson, PhD* and Thomas G. Pickering, MD, DPhil*

* The Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1030, New York, NY 10029-6574, USA

donald.haas{at}msnyuhealth.org


We read with great interest the findings of Henriques et al. (1) regarding worse clinical outcomes for acute myocardial infarction (MI) patients treated with primary angioplasty during off-hours. In their otherwise excellent study, the investigators failed to measure depression or to mention it as another possible reason for the increased rates of failed angioplasty and 30-day mortality observed in those patients presenting between the hours of 1800 and 0800. Depression is common among patients with coronary disease (2), and depressed patients are more likely to develop initial MI symptoms off-hours (3). Depressed patients admitted for MI are at significantly increased risk for mortality (2) and for repeat coronary revascularization (4). Moreover, depression is associated with perturbations of circadian rhythms in patients with and without coronary disease (5). Thus, in addition to the reasons offered by the investigators (1), depression may be another explanation for the worse outcomes observed in patients presenting off-hours.


    References
 Top
 References
 
1. Zwolle Myocardial Infarction Study GroupHenriques JPS, Haasdijk AP, Zijlstra F. Outcome of primary angioplasty for acute myocardial infarction during routine duty hours versus during off-hours. J Am Coll Cardiol. 2003;41:2138–2142[Abstract/Free Full Text]

2. Rozanski A, Blumenthal JA, Kaplan J. Impact of psychological factors on the pathogenesis of cardiovascular disease and the implications for therapy. Circulation. 1999;99:2192–2217[Abstract/Free Full Text]

3. Carney RM, Freedland KE, Jaffe AS. Altered circadian pattern of acute myocardial infarction in patients with depression. Coron Artery Dis. 1991;2:61–65

4. Sullivan MD, LaCroix AZ, Spertus JA, Hecht J, Russo J. Depression predicts revascularization procedures for 5 years after coronary angiography. Psychosom Med. 2003;65:229–236[Abstract/Free Full Text]

5. Carney RM, Freedland KE, Jaffe AS. Insomnia and depression prior to myocardial infarction. Psychosom Med. 1990;52:603–609[Abstract/Free Full Text]




This article has been cited by other articles:


Home page
CirculationHome page
R. Manfredini, B. Boari, P. G. Steg, E. Bonnefoy, P. Touboul, S. Chabaud, A. Leizorovicz, F. Lapostolle, P.-Y. Dubien, and P. Cristofini
Impact of Time to Treatment on Mortality After Prehospital Fibrinolysis or Primary Angioplasty * Response
Circulation, May 11, 2004; 109(18): e219 - e219.
[Full Text] [PDF]


This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Haas, D. C.
Right arrow Articles by Pickering, T. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Haas, D. C.
Right arrow Articles by Pickering, T. G.

 
  CME Topic Collections Past Issues Search Current Issue Home

Advertisement