Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 1 Cypher/ZASP genomic structure. (A) Representation of the Cypher/ZASP genomic structure (top), and six messenger ribonucleic acid isoforms, termed Cypher/ZASP-1, -2, -3, -4, -5, and -6. The PDZ domain is encoded by exons 1, 2, and 3; the three LIM domains are encoded by exons 12-16. (B) The location of mutations identified in this study. Note that the mutation in C/Z1 will also be present in the C/Z2 and 3 isoform (not shown), and the mutation in C/Z4 will also be present in C/Z5 and 6 isoform (not shown).
|
