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Figure 3 Voltage-dependent activation of Ito in mouse ventricular myocytes. Plots showing the voltage-dependence of the current density of Ito,peak at 2-, 4-, 8-, and 9- to 12-month-old cardiomyocytes (A) and Ito,peak-Isus (B). Families of Ito from 4-month-old Ntg (D) and Tg (E, F) myocytes were recorded during a series of voltage clamps from a holding potential of –40 mV to selected test potentials ranging from –40 mV to +80 mV (C).





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