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Figure 2 Change and standard error of the mean from baseline to week 16 in Doppler-derived cardiac index (CI) in bosentan- and placebo-treated patients. The treatment effect was statistically significant for combined dose group (p = 0.007) and for 125 mg (p = 0.019) and 250 mg dose subgroups (p = 0.020). Black bar = bosentan; white bar = placebo.
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