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Figure 4 The forearm blood flow (FBF) variations in response to brachial artery norepinephrine (NE) infusion. Norepinephrine (100, 500, and 1,000 pmol/min) was infused into the brachial artery, and FBF variations (expressed in ml/min per 100 ml) were recorded using venous occlusion plethysmography. The FBF variations are shown before and after S 18886 (top) or placebo (bottom). Statistical analysis was performed on the area under the curve of FBF. No significant differences were observed between the post-treatment values recorded in the S 18886 and placebo groups (analysis of covariance).
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