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Figure 2 Reciprocal interplay between inflammation and diabetes mellitus in the pathogenesis of atherothrombosis, with emphasis on both the role of inflammation in the development of overt diabetes mellitus and the proinflammatory action of hyperglycemia and insulin resistance. Potential or established modulating agents are shown by dashed arrows. ACEi = angiotensin-converting enzyme inhibitors; ARB = angiotensin receptor blockers; PPAR = peroxisome proliferator-activated receptor.
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