Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 1 The pathogenetic mechanisms involved in the initiation of subclinical atherosclerosis and progression to atherosclerotic clinical events in diabetic patients include infection, inflammation, hyperglycemia, insulin resistance, dyslipidemia, and thrombosis. AGE = advanced glycation end products; CRP = C-reactive protein; HDL = high-density lipoprotein; HTN = hypertension; IL-6 = interleukin-6; LDL = low-density lipoprotein; PAI-1 = plasminogen activator inhibitor-1; SAA = serum amyloid A protein; TF = tissue factor; TG = triglycerides; tPA = tissue-type plasminogen activator.
|
