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Figure 4 Positive remodeling in a ruptured plaque. A ruptured plaque (right) is shown, along with a relatively normal adjacent reference segment (left). In the right panel, an interruption of the fibrous cap can be seen with exposure of the underlying lipid core. Compared with the normal reference segment, the external elastic membrane (EEM) area is considerably larger in the segment with plaque rupture than in the adjacent normal reference segment.