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Figure 4 Geometric means (95% confidence intervals) of the ratios of the prothrombin fragment 1+2 (F1+2), thrombin-antithrombin complex (TAT) and ß-thromboglobulin (ß-TG) levels in shed blood collected after administration of 15-, 30- and 60-mg oral doses of ximelagatran compared with control (predose and 2, 4 and 10 h postdose) (n = 12 per marker; three doses x four time points). Predose ratios for each dose, when plasma concentrations are zero, are plotted at 0.001 µmol/l on the logarithmic scale.
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