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Figure 3 Toll-like receptor 4 (TLR4) messenger ribonucleic acid (mRNA) (normalized to 18 S ribosomal ribonucleic acid [rRNA]; mean ± SE, n = 4 to 6) in the heart after lipopolysaccharide (LPS) (1 mg/kg intravenously) injected into rats pretreated for 7 to 10 days with nicotine (6 mg/kg/day) versus saline. Toll-like receptor 4 mRNA increased at 8 to 16 h (*p < 0.05) with no difference between nicotine and saline pretreated rats. Open bar = saline; closed bar = nicotine.
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