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Figure 2 Representative immunofluorescence micrographs of human heart sections labeled for the nicotinamide adenine dinucleotide 3-phosphate (reduced form) oxidase subunit gp91^phox. Panels a, c, e, and g show nonfailing heart tissue and panels b, d, f, and h show end-stage failing tissue. Transverse (a, b) and longitudinal (c, d) sections labeled for gp91^phox show increased labeling in end-stage heart failure. Labeling for alpha-actinin (e, f) shows a typical intracellular pattern of myocyte costamer and intercalated disc labeling. Panels g and h show suprerposition of gp91^phox and alpha-actinin labeling. All scale bars = 20 µm.

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