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Figure 3 Effect of reversing the verapamil (0.02 mg/kg/min)-induced mean arterial pressure (MAP) drop with calcium infusion (3.0 mg/kg/min) on adenosine (A) and ATL-146e (B) flow responses. Note that the vasodilator action of both adenosine and ATL-146e was not restored despite the recovery in MAP, indicating that the blunted coronary flow response was not caused by the verapamil-induced drop in pressure. Data are mean ± SEM of four experiments. *p < 0.05 vs. control.
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