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Figure 3 (A) Increases in p38 MAP kinase, JNK, and ERK activities in each group, compared with the "no ischemia" group, are shown (mean ± SE, n = 3 in each group). These MAP kinases were all activated during ischemia, whereas only p38 MAP kinase was inhibited by infusion of raloxifene into the coronary artery. The activities of the three kinases have been normalized to their total content. *p < 0.01 vs. group with no ischemia.  p < 0.05 vs. group with ischemia.  p < 0.05 vs. group with raloxifene pretreatment without inhibitors (e.g., L-NAME and CTX). (B) Representative results in each kinase are shown.
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