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Figure 1 Effects of valsartan on left ventricular internal diastolic diameter/body surface area (LVIDd/BSA) and ejection fraction (EF) compared to placebo: change from baseline to month of observation. The histobars represent mean changes (adjusted for effects for treatment group, pooled center, baseline value, baseline use of angiotensin-converting enzyme inhibitor or beta blocker, and treatment by baseline value interaction by analysis of covariance) between baseline values and those at months 4, 12, 18, 24, and at end point (last observation available carried forward) for valsartan (black bars) and placebo (white bars). Baseline values at each observation period are adjusted for the number of patients with available data. Change is expressed in absolute units for EF (%) and LVIDd/BSA (cm/m2). The p values for the between-treatment comparison are determined from least-squares mean change.
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