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Figure 2 Induction of ventricular tachyarrhythmias (VTAs) in the long QT syndrome type 2 (LQT2) (A) and long QT syndrome type 3 (LQT3) (B and C) models. During 600-ms basic cycle length pacing, VTA was initiated by a premature beat during left stellate (ganglion) stimulation (LSS) in LQT2 (A). In the LQT3 model, LSS induced multiple premature ventricular complexes and initiated VTA (B). (C) Bradycardia produced by atrioventricular block-dependent VTA. A premature ventricular beat (#) infringed on spatial dispersion of repolarization and created functional conduction block or delayed conduction at the mid-myocardial site (Mid). Endo = endocardial site; Epi = epicardial site.
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