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Figure 2 Hematoxylin- and eosin-stained tissues retrieved from human coronary stent neointima of three different stent age groups. (A-1) Stent neointima at two months after stenting shows hypercellular myxoid tissue characterized by stellate-shaped smooth muscle cells arranged in a disorganized pattern (high-power field, A-2). Smooth muscle cells were identified by immunostaining for  -actin staining of adjacent section (A-3). (B-1) Stent neointima at three months after stenting shows both cell-depleted areas with dense extracellular matrix (ECM) (thick arrow) and a lesion of moderate cellularity with loose ECM (thin arrow). High-power field (B-2) and immunostaining for -actin staining (B-3). (C) Stent neointima at 11 months after stenting shows two kinds of cell-depleted areas: one with dense ECM (thick arrow) and the other with loose ECM (thin arrow). Bar = 100 µm.
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