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Figure 2 Relative risk of major adverse cardiac events according to homocysteine quartiles among total study population and subgroups of patients stratified according to the traditional cardiovascular risk factors. Squares indicates the relative risk (RR) of major adverse cardiac events for patients in the second, third, and fourth homocysteine quartile compared with patients in the first quartile; size of square is proportional to number of patients; and horizontal line indicates 95% confidence interval (CI); RRs are displayed on logarithmic scale. The strongest RR increase between the first and fourth quartile was found in men, smokers, and hypercholesterolemic patients (RR = 3.00, 95% CI = 1.27 to 7.12; RR = 3.50, 95% CI = 0.73 to 9.62; and RR = 2.45, 95% CI = 1.13 to 5.30, respectively).
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