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Figure 4 Ratio of expression level of beta-myosin heavy chain (MHC) messenger ribonucleic acid (mRNA) to alpha-MHC mRNA in the right ventricle in the Control group (n = 12), PH group (n = 17), PH + TA group (n = 18), PH + BPS group (n = 13) and PH + TA + BPS group (n = 18). A typical example of the reverse transcription (RT)-polymerase chain reaction (PCR) product in each group is also shown. *p < 0.05 vs. Control group. §p < 0.05 vs. PH group. #p < 0.05 vs. PH + TA + BPS group. Each column and bar represents the mean value ± SE. BPS = beraprost sodium; PH = pulmonary hypertension; TA = TA-0201.





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