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Figure 1 Changes in the ratio of the minor axis (a) of left ventricle (LV) to the major axis (b) of the LV, an index of pulmonary hypertension (PH), in the parasternal short-axis view of the LV by two-dimensional echocardiography. The view was obtained at the level of the papillary muscle. It was evaluated on days 1, 7, 14 and 19 after the start of treatment. Control group (open circles, n = 12); PH group (solid circles, n = 17); PH + TA group (open squares, n = 18); PH + BPS group (solid squares, n = 13); and PH + TA + BPS group (open diamonds, n = 18). *p < 0.05 vs. Control group.  p < 0.05 vs. PH group. #p < 0.05 vs PH + TA + BPS group. ¶p < 0.05 vs. baseline value of each group on day 1. Data are presented as the mean value ± SE. BPS = beraprost sodium; PH = pulmonary hypertension; RV = right ventricle; TA = TA-0201.
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