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Figure 1 Spectroscopic images of a thin (25 µm), freeze-dried section of vulnerable human carotid atherosclerotic plaque in the near-infrared radiation region. (A) Regular light image of a plaque section. (B to D) Color near-infrared images illustrating the pattern of spectroscopic alteration. Major biochemical components are visualized by wavelength. (B) At 2,225 to 2,550 nm, the contents of cholesterol and cholesterol esters are shown from high to low in red to orange to yellow to green to blue. (C) At 2,200 to 2,225 nm, the contents of protein components (mainly collagen and other matrix proteins) are shown. (D) At 1,720 nm, lipid-rich regions (red) tend to co-localize with regions not in cholesterol (as in B).
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