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Figure 2 (A) Actin staining before left ventricular assist device (LVAD) support shows a severe distortion of the architecture and absence of cross-striation in nearly all myocytes (grade 1). (B) Actin after LVAD support demonstrates some improvement in the staining pattern, with partial restoration of cross-striation (grade 3). (C) Myosin before LVAD support displays a normal architecture (grade 5). (D) After LVAD support, some deterioration is observed (grade 3). (original magnification x250).
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