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Figure 1 Immunohistochemical detection of endothelin-1 (ET-1) in the coronary arteries of the same animal treated with (a) vehicle or (b) the activator protein-1 (AP-1) consensus decoy oligodeoxynucleotide (dODN) 48 h after percutaneous transluminal coronary angioplasty. Positive immunoreactivity for ET-1, both in the periluminal cell layers and in the media, is markedly reduced in the AP-1 consensus dODN-treated artery (original x400, before 00% reduction). The results shown are representative of those obtained with four different animals.
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