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Figure 1 Effects of palmitate on the recovery of cardiac work, cardiac efficiency and pHi of isolated working rat hearts reperfused after ischemia. Values are mean ± SEM of eight glucose-perfused hearts (open circles) and eight glucose+palmitate perfused hearts (closed circles). 31P-NMR measurement of pHi was performed as described in the Methods section. Isolated working hearts were subjected to 20 min of global no-flow ischemia, followed by 40 min of aerobic reperfusion. *Significant time-treatment interaction as determined by two-way analysis of variance with repeated measures on time. After application of the Huyhn-Feldt correction, p values for the time-treatment interactions for cardiac work, cardiac efficiency and pHi are 0.004, 0.007 and <0.0001, respectively.
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