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Figure 1 Left ventricular systolic function in rats with pressure overload hypertrophy (POH). The in vivo pressure–dimension relationship in the pressure overload hypertrophy with heart failure (POH-HF) and pressure overload hypertrophy with no heart failure (POH-NHF) groups exhibits a progressive rightward shift that is most pronounced in the POH-HF group (top). The slope of this relationship (Ees) in the POH-HF group is significantly lower ( 25%) than that in the control group (bottom), although the small reduction (10%) in the POH-NHF group is not significantly less. *p < 0.05 vs. control and POH-NHF groups. CON = sham-operated control group; ESP = end-systolic pressure.
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