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Figure 3 Pharmacologic and postischemic coronary flow velocity reserve (CFVR) increased significantly from 2.1 ± 0.6 to 2.6 ± 0.9, respectively, from 2.7 ± 0.8 to 3.3 ± 1.0 after intravenous administration of 5 mg metoprolol. In two patients, there was no change in pharmacologic CFVR, but in another two patients there was even a decrease in CFVR after beta-blockade. Postischemic CFVR was generally higher than pharmacologic CFVR.
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