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Figure 2 Forearm concentration difference (left) and estimated net release (right) of tissue plasminogen activator (t-PA) antigen (upper, solid lines) and activity (lower, dashed lines) in response to intrabrachial infusion of bradykinin during placebo (open circles), quinapril (closed circles) and losartan (closed squares) administration. p < 0.001 (analysis of variance, ANOVA) for all responses. *p = 0.003, {dagger}p = 0.03, {ddagger}p = 0.09, §p = 0.13 two-way ANOVA: quinapril versus losartan and placebo (p < 0.001 for t-PA response and p = ns for interaction).





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