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Figure 2 Northern blots showing upregulation of expression of a selected differentially expressed gene identified by subtraction hybridization: the upper panels shows blots representing expression of ACTA1, MLC2a, GNAS1, NDUFB10, HSPA8, VDAC1, FHL1 and SARCOSIN in hearts with hypertrophic cardiomyopathy (H) and normal control (N) hearts. The lower panels show the corresponding agarose gels photographs showing 28 S and 18 S ribonucleic acids. ACTA1 = skeletal muscle alpha-actin; FHL1 = four-and-a-half LIM domain protein 1; GNAS1 = GTP-binding protein Gs-alpha subunit; HSPA8 = heat shock 70kD protein 8; MLC2a = myosin light chain 2a; NDUFB10 = reduced nicotinamide adenine dinucleotide ubiquinone oxidoreductase; VDAC1 = voltage-dependent anion channel 1.





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