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Figure 5 (A) Results (mean ± SD) stratified according to percent baseline ischemia. Test variability, indexed by variability index (VI) (refer to the equation in Methods) increases as baseline ischemia increases, so that VI as a proportion of baseline ischemia decreases. (B) Baseline and 12-month follow-up thallium results from subjects who had transmyocardial laser revascularization (TMR) in the ATLANTIC study, stratified according to percent baseline ischemia. Although the data in B suggest TMR may improve myocardial perfusion in subjects with a greater amount of baseline ischemia, data from the ATLANTIC subjects in the continued maximal anti-anginal therapy (MEDs)-only group (C) exhibit the same trends. This suggests a "regression to the mean" phenomenon, as discussed in the text. The p values were derived from paired t tests.
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