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Figure 1 Interaction between Chlamydia pneumoniae (CP) seropositivity and interleukin (IL)-1 gene variants in coronary artery disease (CAD) and myocardial infarction (MI). Regarding CAD prevalence, a stepwise increase was seen depending on seropositivity and the variants. In contrast, MI prevalence was characteristically high in the group with combined seropositivity and variants. The IL-1 gene variants were defined as IL-1ß C/C genotype and/or IL-1 receptor antagonist 2- or 3-repeat allele.
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