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Figure 8 Direction of remodeling and temporal development of plaques. Positive remodeling may be a characteristic of early, unstable lesions, allowing considerable plaque accumulation despite normal luminal size. Negative remodeling and fibrotic changes may be associated with more stable plaques. The observation of remodeling in relation to clinical presentation may be important in the assessment of plaque vulnerability and stabilization. EEM = external elastic membrane.
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