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Figure 5 Histomorphologic analysis of infarcted and noninfarcted segments. Microscopic sections from the infarcted (A) and noninfarcted (B) segments stained with picrosirius red are shown. On the top panels, dark red stained areas represent collagen replacement, and in the lower panels, green/yellow areas represent birefringence of collagen under polarized light. The infarcted segment (transmural scar by gross pathology) demonstrates morphologically normal appearing myocytes that could not be detected by thallium scintigraphy or by gross pathology. Conversely, a microscopic section from the noninfarcted segment (normal by gross pathology) shows layers of collagen within normal appearing myocytes that could not be detected by thallium scintigraphy or gross pathology.
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