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Figure 1 Time course of anti-endotoxin core antibodies perioperatively in patients undergoing coronary artery bypass graft surgery without adverse events (groups 1A and 1B) compared with that in patients with prolonged mechanical ventilation time (group 2) (mean value ± SD). Time points: 1) preoperative; 2) induction of anesthesia; 3) sternotomy; 4) cardiopulmonary bypass onset; 5) protamine reversal; 6) skin closure; 7) 30 min postoperatively; 8) 3 h postoperatively; 9) 24 h postoperatively; 10) 48 h postoperatively; and 11) 72 h postoperatively. *p < 0.01. Ig = immunoglobulin; LPS = lipopolysaccharide.





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