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Figure 4 Effects of chronic treatment with the angiotensin-converter enzyme inhibitor ramipril (1 mg/kg/day), the AT1 receptor antagonist valsartan (10 mg/kg/day) and the AT2 receptor antagonist PD 123319 (30 mg/kg/day) on protein levels of Na+-H+ exchanger isoform-1 (NHE-1) (A) and Na+-HCO3– symporter isoform-1 (NBC-1) (B) in the left ventricular free wall one day and seven days after myocardial infarction (MI) compared with sham-operated and placebo-treated animals with MI. *p < 0.05 compared with sham operation; #p < 0.05 compared with placebo MI. Data represent mean ± SEM, n = 6. PD = PD 123319; Pl = placebo; Ra = ramipril; Sh = sham-operated; Va = valsartan.
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