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Figure 3 Distribution of multiple measurements of aortic wall thickness in normal subjects by transesophageal magnetic resonance imaging. Aortic wall thickness (excluding adventitia) was measured in 82 locations in multiple transesophageal magnetic resonance images from normal subjects using National Institutes of Health Image 1.62 and allowing multiple measurements per individual. The distribution appears Gaussian, with mean = 1.03 mm; standard deviation (SD) = 0.32 mm; mean + 2 SD = 1.67 mm; mean + 3 SD = 1.99 mm. In subsequent subjects, abnormal thickness was arbitrarily defined as mean + 3 SD (i.e.,  2.0 mm). The circumferential extent of disease was defined as the number of degrees (of 360) over which the wall thickness was abnormal.
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