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Figure 2 Absolute changes from the baseline in plasma levels of aldosterone (ALD), brain natriuretic peptide (BNP), and procollagen type III aminoterminal peptide (PIIINP) before and after treatment with placebo or spironolactone for four months in patients with mild-to-moderate congestive heart failure. *p < 0.05; **p < 0.01 versus placebo.
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