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Figure 5 Comparison of the differences before and after epinephrine in the max QTc-e (A), min QTc-e (B), QTc-eD (C), max QTc-p (D), minQTc-p (E), and QTc-pD (F), which were obtained from 87-leads, in LQT1, LQT2, and control groups. Changes in the max QTc-e with epinephrine were largest in LQT1 patients, intermediate in LQT2 patients, and were not significant in control patients (A), whereas changes in the min QTc-e were not different between LQT1 and LQT2 patients, but were significantly larger than those in control patients (B). As a consequence, changes in the QTc-eD were larger in LQT1 patients than those in LQT2 and control patients (C). In contrast, no significant differences were seen in the changes in the max QTc-p (D), min QTc-p (E), and QTc-pD (F) among the three groups.





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