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Figure 1 Twenty-four-lead ECGs (G–K: 2–6) that are expected to reflect the potential from the left ventricular free wall under baseline condition (A) and during epinephrine infusion (B) in a patient (pt) with LQT1 syndrome. A representative ECG (H4) is shown on the upper trace in each panel. The ECGs showed broad-based T waves commonly observed in LQT1 patients. Both the QTc-e and QTc-p were prolonged (603, 482 ms1/2) and the Tcp-e was increased (121 ms1/2) under the baseline condition (A). Epinephrine produced a prominent prolongation in the QTc-e (712 ms1/2), but a mild prolongation in the QTc-p (520 ms1/2), resulting in a dramatic increase in the Tcp-e (192 ms1/2) (B).
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