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Figure 7 Representative Western blot analysis demonstrating the effect of simvastatin (10–5 mol/liter) on eNOS expression in TNF-alpha–stimulated (500 U/ml) human neutrophils. Expression of eNOS was determined 8 h after TNF-alpha stimulation. (Densitometric analysis in arbitrary units—basal: 100*; TNF-alpha: 23 ± 8; TNF-alpha + simvastatin 10–5 mol/liter: 211 ± 19*; [n = 6]; *p < 0.05 vs. TNF-alpha–incubated neutrophils.) eNOS = endothelial-type nitric oxide synthase.
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