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Figure 2 A representative case (case 1). At baseline (day 1), the hyperventilation (HV) test induced anginal attacks with ST segment elevation in leads II, III and aVF and depression in leads I and aVL (A), but not after estradiol (E2) supplementation (day 3) (B). After placebo administration (day 5), the HV test again induced anginal attacks with ST segment elevation in leads II, III and aVF and depression in leads I and aVL (C).





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