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Figure 1 Pedigrees of families 1012 and 1034. Squares represent males, circles are females and symbols with slash mark represent deceased subjects. Half-filled symbols indicate heterozygous KCNQ1-Fin carriers, filled symbols homozygous KCNQ1-Fin carriers and half-striped symbols are heterozygous Y171X carriers. Open symbols denote unaffected individuals verified by deoxyribonucleic acid (DNA) assay. Subjects IV/6 and IV/8 in family 1012 and III/7 in family 1034 have Jervell and Lange-Nielsen syndrome (JLNS). The QTc interval (ms) is shown under each symbol; those marked with an asterisk have been recorded during medication.





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