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Figure 5 Percent change in platelet cGMP content during in vitro incubation with acetylcholine, sodium nitroprusside and L-NMMA is shown in open circles. For comparison, the effect of these agonists at estimated intracoronary concentrations achieved during in vivo administration in the normal subjects are shown in closed circles. *p 0.05, **p < 0.001 compared to baseline. cGMP = cyclic guanosine monophosphate; L-NMMA = L-NG monomethyl arginine.
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