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Figure 1 Photomicrographs of week 8 coronary arteries stained with hematoxylin-eosin. Large epicardial coronary arteries (top) and downstream microvascular arterioles (middle; 50 µm ≤lumen diameter <150 µm; bottom; lumen diameter <50 µm). Left panel is from the Control group, center panel from the ED group and right panel from the Drug group. In the ED group, thickening of the media and increased perivascular fibrosis are shown. Epicardial coronary arteries in the center and right upper panels show the denuded portions. Scale bars indicate 100 µm.





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