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Figure 1 The histology of porcine coronary arteries 72 h after angioplasty. (A and B) coronary sections of vehicle-treated animals showing the presence of mural thrombus (red arrows). (C and D) sections of recombinant tissue factor pathway inhibitor plus heparin-treated animals. Note the hemorrhagic area surrounding the coronary wall (yellow arrows). (E and F) sections of recombinant tissue factor pathway inhibitor alone-treated animals, with no mural thrombosis and no periarterial hemorrhage. Note the comparable degrees of injury, with disruption of the internal elastic lamina in all sections. (All sections photographed at 40x).
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