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Figure 3 Increased apoptosis activity with oral RGD glycoprotein IIb/IIIa inhibitors. (A) Time dependent increase in apoptosis in rat neonatal cardiomyocytes over 24 to 72 h. (B) Dose-dependent increase in apoptosis in rat neonatal cardiomyocytes observed with low-dose (3 µM), moderate-dose (10 µM) and high-dose (30 µM) of orbofiban or xemilofiban. *p < 0.01;  p < 0.001. Reproduced with permission from Adderley et al (46).
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