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Figure 5 Top: Western blot depicting the expression of Bcl-2 in three normal (NL) dogs and three untreated dogs with heart failure (HF). Bottom: Western blot depicting the expression of Bcl-2 in five dogs with heart failure that were untreated (HF) and five dogs with HF that were treated with metoprolol (HF-MET). Western blots were performed at different times for MET-treated versus untreated dogs with HF and for untreated dogs with HF versus NL dogs and, therefore, while directionally consistent, the band density measurements are not directly comparable due to different exposure times.
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