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Figure 1 Panels A, B and C: Section of left ventricular myocardium showing cardiomyocytes bordering scar tissue from an untreated dog with heart failure (magnification x 750). (A) Shows a cardiomyocyte positively stained (red) with antimyosin antibody, identifying the cell as a cardiomyocyte. The unstained center region is the nucleus. (B) Shows the same cardiomyocyte nucleus stained positively (blue) with the specific nuclear stain Hoechst 33342. (C) Shows the same left ventricular section as in (A) and (B). The nucleus is positively stained (yellow-green) for nuclear DNA fragmentation.





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