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Figure 1 Hypoxia-reoxygenation induces Ca2+ loading in both female and male cardiomyocytes. Time-course (left and central panels) of fluorescence in Fluo-3 loaded female and male cardiomyocytes exposed to hypoxia-reoxygenation, with average concentrations of intracellular Ca2+ prior and following hypoxia-reoxygenation (right panel). Bars represent mean ± SEM (n = 13–14). Hypoxia-reoxygenation was induced by application (3 min at 37°C), and removal of 2 mmol/liter DNP.
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